If a modified APK somehow bypasses the root check inside the app's interface, it will simply crash the moment you try to host an ISO file, because the Android system will deny its hardware requests.
Android app:
This app can write ISO files to a connected USB drive without root access. Works on non-rooted phones. drivedroid no root apk
Download your preferred Linux or Windows ISO file directly onto your phone's internal storage. If a modified APK somehow bypasses the root
You might see "no root" tutorials for DriveDroid involving these methods: drivedroid no root apk